The 21st ACIS International Semi-Virtual Winter Conference on Software Engineering, Artificial Intelligence, Networking and Parallel/Distributed Computing (SNPD2021-Winter) brings together researchers, scientists, engineers, industry practitioners, and students to discuss, encourage and exchange new ideas, research results, and experiences on all aspects of computer and information science. SNPD2021 Winter aims to facilitate cross-fertilizations among the key technology enabling areas and is soliciting papers in these areas.